Title: Studies on the interrelations between the pollution by polychlorinated biphenyls and thyroid gland 
Resource Type: document --> technical publication --> proceedings / conference paper(s) 
Country: EU Projects 
Year of publication: 2003 
Availability: Langer, P. et al. (2003) Studies on the interrelations between the pollution by polychlorinated biphenyls and thyroid gland. Persistent Toxic Substances Contamination of the European Region as a reflection of results of the GEF/UNEP Regional Based Assessment of Persistent Toxic Substances (RBA PTS) in Europe, the implementation of the Stockholm Convention and 'Community Strategy for Dioxins, Furans and PCBs 
Author 1/Producer: Langer, P. 
Other Authors/Producers: Šeböková, E., Kočan, A., Hučková, M., Tajtáková, M. 
Author / Producer Type: EC Project 
Report / download web link (=direct link): http://www.recetox.muni.cz/coe/sources/workshop_1_rba_pts/IV ...  
Format (e.g. PDF): PDF 
EUGRIS Keyword(s): Diffuse pollution-->Contaminants-->Persistent Organic Pollutants
Short description: Objective. The aim was to obtain information about some fundamental interrelations between heavy pollution by polychlorinated biphenyls (PCB) as evaluated in terms of their blood level and the thyroid volume and function as evaluated by ultrasound and levels of hormones and anti-thyroperoxidase autoantibodies in blood. Subjects and Methods. In the area of heavy environmental pollution by PCB (POLL) a total of 1008 adults were examined, while in the area with background pollution (BACK) the number of examined was 1038. In addition to several data obtained by questionnaires, the thyroid volume (ThV) was estimated by ultrasound (using the ellipsoid method) and several hormones (thyrotropin -TSH, total triiodothyronine – TT3, free thyroxine – FT4) and anti-thyroperoxidase autoantibodies (anti-TPO) were estimated in serum with the use of highly sensitive electrochemiluminiscent method. In this presentation also the data are used on the estimation of total PCB by congener specific assay using gas chromatography and mass spectrometry. 
Link to Project(s): RECETOX Centre of Excellence in Environmental Chemistry and Ecotoxicology
Submitted By: Dr Stefan Gödeke WhoDoesWhat?      Last update: 14/02/2006

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