| Title: |
Multianalyte determination of different classes of pesticides (acidic, triazines, phenyl ureas, anilines, organophosphates, molinate and propanil) by liquid chromatography-electrospray-tandem mass spectrometry
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| Resource Type: |
document --> technical publication --> journal article
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| Country: |
EU Projects
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| Year: |
2004 |
| Availability: |
Borba da Cunha, Ana C et al. (2004) Multianalyte determination of different classes of pesticides (acidic, triazines, phenyl ureas, anilines, organophosphates, molinate and propanil) by liquid chromatography-electrospray-tandem mass spectrometry
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| Author 1/Producer: |
Borba da Cunha, Ana C
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| Other Authors/Producers: |
López de Alda, Maria J.
Barceló, Damià
Pizzolato, Tania M.
dos Santo, Joao Henrique Z
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| Author / Producer Type: |
EC Project
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| Format (e.g. PDF): |
PDF
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EUGRIS Keyword(s): |
Contaminated land-->Contaminants-->Contaminants overview
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| Short description: |
This work describes the optimization of a liquid
chromatography-electrospray-tandem mass spectrometry
(LC-ESI-MS-MS) method for the multianalyte determination
of twenty pesticides, selected based on current
regulations and extent of use. Chromatographic separation
was carried out on a Purospher STAR RP-18e column using
gradient acetonitrile-water as mobile phase. Triazines,
phenylureas, organophosphates, anilines, and molinate were
determined in the positive ionization mode, and acidic
pesticides and propanil in the negative ion mode. Two different
precursor ion-product ion transitions were selected
for each analyte and monitored under time scheduled multiple
reaction monitoring (MRM) conditions. The optimized
method was shown to be linear in the range 1 to
1000 ng/mL with correlation coefficients higher than 0.99
for all but one (diazinon) of the analytes, very sensitive
(with limits of detection between 0.010 and 4.528 ng/mL),
and repeatable (with relative standard deviations, calculated
from the replicate analysis of standard mixtures,
lower than 14%). The present work was also devoted to
the elucidation of the structures of the principal fragment
ions obtained after collision-induced dissociation of the
pesticides investigated, an aspect often overlooked in the
literature.
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Submitted By:
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Dr Stefan Gödeke WhoDoesWhat?
Last update: 14/02/2006
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