| Title: |
Assessment of migration of non-suspected compounds from products in contact with drinking water by GC-MS
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| Resource Type: |
document --> technical publication --> report
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| Country: |
EU Projects
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| Year: |
2003 |
| Availability: |
James, H. et al. (2003) Assessment of migration of non-suspected compounds from products in contact with drinking water by GC-MS, EU Report 20833
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| Author 1/Producer: |
James, H.
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| Other Authors/Producers: |
Bondant, M., Hoekstra, E.J., Langer, S., Noij, Th., Stottmeister, E., Veschetti, E.
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| Author / Producer Type: |
EC Project
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| Report / download web link (=direct link): |
http://www.jrc.cec.eu.int
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| Format (e.g. PDF): |
PDF
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EUGRIS Keyword(s): |
Water and sanitation-->Water and sanitation Overview
Water resources and their management -->Water resources and their management Overview
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| Long description: |
GCMS analysis is undertaken to determine whether organic chemicals not specified in the
formulation of CPDW materials migrate into drinking waters. The harmonisation of the
GCMS assessment needs to be studied to decide on the comparability of data produced
by different laboratories using different equipment, when all laboratories use the same
protocol. Initially an assessment is required of the rigidity of the protocol in order to ensure
good comparability of data, and the agreed (and if necessary, modified) protocol needs to
be applied to real migration waters from CPDW materials to allow its effectiveness to be
assessed.
Initial work programme
Only France and the UK routinely apply GCMS to detect unsuspected organic chemicals
(unspecified compounds) in migration waters from CPDW materials in their national
approval schemes. Although the two procedures are similar in many ways, there are some
important differences that need to be harmonised. One should bear in mind that the
current GCMS assessment procedures (France and UK) are a necessary compromise
between generating data on products and excessive costs. Additional advanced
techniques could be applied to address some of the limitations of the GCMS approach,
but the harmonised methodology must be practical and not limited to just a few research
laboratories.
The work programme initially proposed was as follows:
Stage 1 – Harmonisation of the basic GCMS procedure
In this stage, all participating laboratories assessed the practicality of the GCMS protocol
described in the UK BS6920: Part 4. A range of compounds was to be chosen for this
purpose.
Stage 2 – Selection of the solvent extraction procedure
As the procedures routinely used by France and the UK were slightly different, the two
procedures were compared to ascertain which was the better of the two.
Stage 3 – Selection of possible SPE procedure
As solid phase extraction (SPE) is increasingly used for the analysis of many organic
compounds in water, and for various reasons (e.g. ease of automation, reduction in
solvent usage) is now preferred to solvent extraction, it was considered appropriate to
establish whether this offered a viable alternative for this particular application. Two
different types of SPE material were compared to ascertain whether either were suitable.
Stage 4 – Comparison of preferred solvent extraction and SPE procedures
Assuming that one of the SPE procedures studied in Stage 3 was comparable to the
preferred solvent extraction procedure (from Stage 2), then it would be necessary to
directly compare the different extraction techniques to assess which was the most
appropriate for the analysis of migration waters from CPDW materials. If neither of the
SPE procedures tested in Stage 3 gave results that were comparable to the preferred
solvent extraction procedure, then this stage would not be undertaken.
Stage 5 – Investigation of the overall preferred GCMS assessment procedure
In this stage all participating laboratories were to analyse extracts from migration waters
from epoxy resin, GRP, cement with organic additive and rubber. Four participants were
to prepare the migration waters, using chlorinated and unchlorinated water, and carry out
the extractions to prepare extracts. These extracts were to be circulated to all of the
participants for GCMS analysis.
10
Stage 6 – Establishment of a GCMS database and preparation of final report
To facilitate the use of the GCMS assessment procedure developed, the most useful
design and operation of a GCMS database relating to materials in contact with drinking
water will be discussed and recommended. Its value compared to existing databases
would be assessed.
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Submitted By:
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Dr Stefan Gödeke WhoDoesWhat?
Last update: 10/10/2006
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