| Title: |
Transgenerational epigenetic imprints on mate preference
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| Resource Type: |
document --> technical publication --> journal article
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| Country: |
USA
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| Year: |
2008 |
| Availability: |
Proc Nat Acad Sci 104 5942-5946
Published online on March 26, 2007, 10.1073/pnas.0610410104
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| Author 1/Producer: |
David Crews
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| Other Authors/Producers: |
Andrea C. Gore, Timothy S. Hsu, Nygerma L. Dangleben, Michael Spinetta, Timothy Schallert, Matthew D. Anway and Michael K. Skinner
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| Author / Producer Type: |
University research group / research institute
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EUGRIS Keyword(s): |
Contaminated land-->Risk assessment-->Receptor: Human health
Contaminated land-->Risk assessment-->Toxicological information
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| Short description: |
Extract: Environmental contamination by endocrine-disrupting chemicals (EDC) can have epigenetic effects (by DNA methylation) on the germ line and promote disease across subsequent generations. In natural populations, both sexes may encounter affected as well as unaffected individuals during the breeding season, and any diminution in attractiveness could compromise reproductive success. Here we examine mate preference in male and female rats whose progenitors had been treated with the antiandrogenic fungicide vinclozolin.
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Submitted By:
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Professor Paul Bardos WhoDoesWhat?
Last update: 06/03/2008
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