| Title: |
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location
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| Resource Type: |
document --> technical publication --> journal article
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| Country: |
Canada
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| Year: |
2008 |
| Availability: |
Proc Nat Acad Sci 105 605-610
Published online on January 14, 2008, 10.1073/pnas.0705896105
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| Author 1/Producer: |
Carole Yauk
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| Other Authors/Producers: |
Aris Polyzos, Andrea Rowan-Carroll, Christopher M. Somers,, Roger W. Godschalk, Frederik J. Van Schooten, M. Lynn Berndt, Igor P. Pogribny, Igor Koturbash, Andrew Williams, George R. Douglas, and Olga Kovalchuk
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| Author / Producer Type: |
University research group / research institute
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EUGRIS Keyword(s): |
Contaminated land-->Risk assessment-->Toxicological information
Diffuse pollution-->Contaminants-->Contaminants overview
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| Short description: |
Extract: Particulate air pollution is widespread, yet we have little understanding of the long-term health implications associated with exposure. We investigated DNA damage, mutation, and methylation in gametes of male mice exposed to particulate air pollution in an industrial/urban environment. C57BL/CBA mice were exposed in situ to ambient air near two integrated steel mills and a major highway...
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Submitted By:
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Professor Paul Bardos WhoDoesWhat?
Last update: 06/03/2008
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