Title: Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location 
Resource Type: document --> technical publication --> journal article 
Country: Canada 
Year: 2008 
Availability: Proc Nat Acad Sci 105 605-610 Published online on January 14, 2008, 10.1073/pnas.0705896105 
Author 1/Producer: Carole Yauk 
Other Authors/Producers: Aris Polyzos, Andrea Rowan-Carroll, Christopher M. Somers,, Roger W. Godschalk, Frederik J. Van Schooten, M. Lynn Berndt, Igor P. Pogribny, Igor Koturbash, Andrew Williams, George R. Douglas, and Olga Kovalchuk 
Author / Producer Type: University research group / research institute 
Article Weblink (=direct link): http://www.pnas.org/cgi/content/full/105/2/605  
EUGRIS Keyword(s): Contaminated land-->Risk assessment-->Toxicological information
Diffuse pollution-->Contaminants-->Contaminants overview
Short description: Extract: Particulate air pollution is widespread, yet we have little understanding of the long-term health implications associated with exposure. We investigated DNA damage, mutation, and methylation in gametes of male mice exposed to particulate air pollution in an industrial/urban environment. C57BL/CBA mice were exposed in situ to ambient air near two integrated steel mills and a major highway... 
Submitted By: Professor Paul Bardos WhoDoesWhat?      Last update: 06/03/2008

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